MicroRNA-21 as a biomarker for ovarian cancer detection
نویسندگان
چکیده
منابع مشابه
Investigation of MicroRNA-21 Expression Levels in Serum and Stool as a Potential Non-Invasive Biomarker for Diagnosis of Colorectal Cancer
Background: Most cancer studies focus on exploring non-invasive biomarkers for cancer detection. In the present study, we sought to investigate the expression level of microRNA-21 (miR-21), as a potential diagnostic marker, in serum and stool samples from 40 patients with colorectal cancer (CRC) and 40 healthy controls. Methods: Quantitative real-time RT-PCR was applied to determine the relativ...
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Studies have shown cell-free microRNA (miRNA) circulating in the serum and plasma with specific expression in cancer, indicating the potential of using miRNAs as biomarkers for cancer diagnosis and therapy. This study was to investigate whether plasma miRNA-21 (miR-21) can be used as a biomarker for the early detection of non-small cell lung cancer (NSCLC) and to explore its association with cl...
متن کاملRole of microRNA as a biomarker in Alzheimer’s disease
Introduction: MicroRNAs are small, non-coding, and protected RNA molecules that regulate gene expression after transcription by mRNA degradation or inhibition of protein synthesis. The function of these molecules is critical to many cellular processes, including growth, development, differentiation, homeostasis, apoptosis, aging, stress resistance. In addition, some diseases including cancer, a...
متن کاملMicroRNA‐135a‐3p as a promising biomarker and nucleic acid therapeutic agent for ovarian cancer
Ovarian cancer is the most lethal gynecologic malignancy. Recently, several molecularly targeted anticancer agents have been developed for ovarian cancer; however, its prognosis remains extremely poor. The development of molecularly targeted therapy, as well as companion diagnostics, is required to improve outcomes for patients with ovarian cancer. In this study, to identify microRNAs (miRNAs) ...
متن کاملmicroRNA-21 and microRNA-375 from oral cytology as biomarkers for oral tongue cancer detection.
OBJECTIVE We previously performed a meta-analysis of microRNA profiling studies on head and neck/oral cancer (HNOC), and identified 11 consistently dysregulated microRNAs in HNOC. Here, we evaluate the diagnostic values of these microRNAs in oral tongue squamous cell carcinoma (OTSCC) using oral cytology samples. MATERIALS AND METHODS The levels of 11 microRNAs were assessed in 39 oral cytolo...
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ژورنال
عنوان ژورنال: Indonesian Journal of Biotechnology
سال: 2018
ISSN: 2089-2241,0853-8654
DOI: 10.22146/ijbiotech.35692